Organic Chemistry

B.Sc. & M.Sc. Organic Notes:

M.Sc/Graduate and B.Sc/Undergraduate Organic Chemistry notes,download free. Analytical, Physical, Inorganic and General chemistrylecture/ course notes on DOWNLOAD page or hover over DOWNLOAD tab. Comeback to download complete notes.
 

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B.Sc.& M.Sc. Organic Notes:

1.                   Aromatic - Aromaticity, Homoaromaticity, Antiaromatic – Annulenes, Aromaticity in charged rings,  Benzene – Kekulé, Hückel 4n+2 Rule, Fused ring systems, Azulene, Acenaphthylene, Aromaticity of heterocycles,  Electrophilic aromatic substitutions, arenium ion mechanism, The SE1 mechanism, Electrophilic aromatic substitutions, Reactivity of heteroaromatic compounds, Electrophilicsubstitutions,Electrophilic aromatic substitutions of metallated aromatics – Electrophilic substitutions involving hydrogen-lithium exchange, Electrophilic substitutions of Aryl-Grignard (Aryl-Lithium) reagents, Nucleophilic aromatic substitution – The addition-elimination mechanism (Meisenheimer complexes), Nucleophilicsubstitution of diazonium salts, The elimination-addition mechanism (benzyne intermediate), Spectroscopy of Aromatic Compounds – (a)DOWNLOAD (b) DOWNLOAD (c) DOWNLOAD (d) DOWNLOAD

2.                   Stereochemistry - Enantiomers and Chirality, 3-D Representations of Enantiomers, Properties of Chiral Molecules- Optical Activity, Chiral centers and chiral molecules, Conformations and chirality, assigning absolute configuration, Representations of R and S Structures, R/S nomenclature system, Assigning absolute configuration in cyclic molecule, Assigning absolute configuration in fischer formula, Translating 3-D formulas into fischer formula, Diastereomers and meso form, summary of relationship between molecules with 2 or more chiral centre, shortcut for assigning absolute configuration on paper, Cahn-Ingold-Prelog Sequence Rules, D and L Notation, Configurations of D-Aldose, Configurations of Ketose, Reactions of Monosaccharides – (a) DOWNLOAD (b) DOWNLOAD (c)DOWNLOAD (d) DOWNLOAD (e) DOWNLOAD (f) DOWNLOAD

3.                   Conformational analysis – introduction of terms – conformers, configuration, dihedral angle, torsional strain – Conformational analysis of ethane and n-butane including energy diagrams – conformers of cyclo hexane (chair, boat and skew boat forms) – axial and equatorial. Bonds-ring flipping showing axial equatorial inter conversions – conformers of mono and id substituted cyclohexanes – 1:2 and 1:3 interactions , Conformations of Other Cycloalkanes,strain, anomeric effect,Naming Polycyclic Ring Systems, Stereochemistry of Polycyclic Ring Systems – (a) DOWNLOAD (b)DOWNLOAD

4.                   Asymmetric synthesis - Stereoselective synthesis – Chemoselectivity, Regioselectivity, Stereoselectivity – (a)DOWNLOAD (b) DOWNLOAD (c) DOWNLOAD (d) DOWNLOAD

5.                   Carbonyl group chemistry - Reactivity of carbonyl group – alphasubstitution of enol, Acidity of a-Hydrogen atoms,  Aldehyde and Ketone – Addition Reaction of the carbonyl group,Mechanisms of Aldol, Perkin, Knoevenagal reactions and benzoin condensation – Claisen, Wiffig, Cannizaro, Reformatsky reactions, Mechanisms of reduction with (sodium boro hydride, LiAlH₄, Woiff-Kishner and MPV) – mechanisms of haloform reaction and Michael addition, Carboxylic Acid and their derivative reactions – Conversion of acids to their derivatives, Dicarboxylic acids – Preparation and properties of oxalic, malonic. succinic, glutaric and adipic acids, Malonic and acetoacetic esters characterstic reactions of active methylene group – synthetic uses of malonic ester, acetoacetic ester and cyanoacetic ester,Enols, Enolates  and polycarbonyl compounds Tautornerism – definition – keto-enol tautomerism (identification, acid and bae catalysed inter – conversion mechanism, preparation and characterstics) – amidoimidol and nitroacinitro tautomerism – (a)DOWNLOAD (b) DOWNLOAD (c) DOWNLOAD (d) DOWNLOAD (e)DOWNLOAD (f) DOWNLOAD (g) DOWNLOAD (h) DOWNLOAD

6.                   Alkane, Alkylation – Nomenclature, isomers, basic chemical reactions,substitution, elimination, electrophilic addition, alkane – From other acetylenes, from carbonyls, from olefins, from Strained Rings, Eschenmosher Fragmentation Allenes, Alkylation – Alkylation of enolates, enamines and hydrazones,  Alkylation of heteroatom stabilized anions, Organometallic Reagents, Sigmatropic Rearrangements, olefin reactions – Aldol Condensation, Wittig Reaction, Peterson Olefination,  Julia-Lythgoe Olefination, Carbonyl Coupling Reactions,  Tebbe Reagent, Shapiro and Related Reaction,  beta-Elimination and Dehydration, From Diols and Epoxides, From Acetylenes, From Other Alkenes-Transition Metal Catalyzed Cross-Coupling and Olefin Metathesis, basic chemistryproblem solving approach (a) DOWNLOAD(b) DOWNLOAD(c)DOWNLOAD (d) DOWNLOAD (e) DOWNLOAD

7.                   Oxidation-Reduction reactions and protecting groups –Different oxidation reactions,  and reagents – Covers almost all the oxidation reactions and oxidizing reagents, oxidation metal Based Reagents,  Non-Metal Based Reagents,  others and  Epoxidations, Different reduction reactions,  and reagents – Covers almost all the reduction reactions and reducing reagents, Different protecting groups and reaction involving each, Hydroxyl groups,  Ketones and aldehydes,  Amines and Carboxylic Acids – (a) DOWNLOAD (b)DOWNLOAD (c) DOWNLOAD (d) DOWNLOAD (e) DOWNLOAD

8.                   Reaction Mechanism - common organic reactions with mechanism, writing reaction mechanism, kinds of organic reactions, homolysis, hetrolysis, bond dissociation energy, kinetics, nucleophilic aromaticsubstitution, alkyl halide elimination reaction, β-elimination (most common elimination reaction), useful reaction to synthesize alkenes, alkynes, other π bond functional groups, E1 and E2 with mechanism and example, Mechanism and stereochemistry of E1 and E2 reaction – (a) DOWNLOAD (b)DOWNLOAD (c) DOWNLOAD (d) DOWNLOAD(e) DOWNLOAD (f) DOWNLOAD (g) DOWNLOAD (h) DOWNLOAD